Ernst Mühlstein was a Jewish architect who worked in Prague in the 1920s and 1930s. He studied at the Prague German Technical University and later with Jan Kotěra at the Academy of Fine Arts in Prague.
In 1924, he founded a studio for architecture together with Victor Fürth. In the 1920s and 1930s, they built a number of villas from Neo-Baroque to Modernism mainly in Prague, but also in other towns in Czechia and one in Cortina d'Ampezzo, Italy. They also designed apartment buildings, including small apartment buildings for social housing. Before World War II he emigrated in 1939 to the UK and later to Australia. There he changed his name to Ernst Edward Milston. His estate belongs to the archives of the University of Melbourne.